ChemCo MOTS-c 20mg Pen – High-Purity Research Compound

The ChemCo MOTS-c 20mg Pen delivers a pre-formulated, analytical-grade presentation of MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) engineered specifically for metabolic signaling studies, AMP-activated protein kinase (AMPK) activation assays, cellular energy homeostasis models, and mitochondrial-nuclear communication research. Containing 20mg of high-purity synthetic 16-amino-acid peptide, this pre-filled dialable pen format eliminates manual reconstitution variables and guarantees exact volumetric precision across long-horizon laboratory protocols.

Technical Specifications & Chemical Profile

• Product Identifier: ChemCo MOTS-c 20mg Pen

• Active Compound: MOTS-c (Mitochondrial-Derived Peptide)

• Total Concentration: 20mg per pen unit

• Chemical Class: Mitochondrial-Encoded Signaling Polypeptide (MDP)

• CAS Registry Number: 1627580-64-6

• Molecular Formula: $C_{101}H_{152}N_{28}O_{22}S_2$

• Molecular Weight: ~2174.6 g/mol

• Amino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR)

• Purity Threshold: ≥98% (HPLC & LC-MS Verified)

• Delivery Format: Precision Dialable Multi-Dose Pen Presentation

For tissue remodeling and extracellular matrix studies, explore our ChemCo 150mg GHK-Cu Pen or review our complete line on the main ChemCo Peptides Hub.

Technical Advantages of the MOTS-c 20mg Pen Presentation

Selecting a pre-filled mots-c 20mg pen UK inventory unit delivers distinct operational and analytical benefits for research teams:

1. Elimination of Lyophilized Reconstitution: Pre-mixed liquid stabilization avoids fluid volume errors, solubility degradation, or equipment contamination during manual dilution.

2. Precision Micro-Dosing: Calibrated mechanical dial wheel permits step-wise micro-litre adjustments for exact dosage control across multi-sample testing protocols.

3. Enhanced Sequence Protection: Sealed inner cartridge shields the methionine-rich sequence from atmospheric oxidation and light-induced degradation.

Mitochondrial Signaling & Metabolic Research Applications

When evaluating chemco mots-c research pen samples, researchers examine a unique mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene that regulates metabolic homeostasis:

                        ┌──> AMPK Phosphorylation & AICAR-like Pathway Activation
                        │
ChemCo MOTS-c 20mg ─────┼──> Nuclear Translocation under Metabolic Stress
(16-Amino-Acid MDP)     │
                        └──> Folate Cycle Modulation & De Novo Purine Biosynthesis

1. AMPK Activation & Metabolic Homeostasis

MOTS-c acts centrally on metabolic pathways by activating AMP-activated protein kinase (AMPK) independent of upstream intracellular ATP/AMP ratios, making it a primary benchmark compound for metabolic research.

2. Retrograde Mitochondrial-to-Nuclear Communication

Investigated for its ability to translocate to the nucleus during metabolic stress conditions (e.g., nutrient deprivation or oxidative stress), regulating nuclear gene expression and cellular adaptation.

3. Insulin Sensitivity & Glucose Utilization Models

Enables cellular study into glucose transporter 4 (GLUT4) translocation, fatty acid oxidation dynamics, and systemic insulin sensitivity signaling pathways.

Quality Control & Analytical Batch Testing

Every mitochondrial peptide pen distributed by ChemCo Medical is backed by batch-specific, verifiable analytical documentation:

• High-Performance Liquid Chromatography (HPLC): Guarantees active sequence purity meets or exceeds 98%, confirming freedom from truncated fragments.

• Liquid Chromatography-Mass Spectrometry (LC-MS): Verifies exact molecular mass (2174.6 Da) and correct 16-amino-acid sequence profile.

• Sterility & Endotoxin Inspection: Processed under strict laboratory controls to ensure low endotoxin levels suitable for sensitive in vitro assays.

Storage & Handling Guidelines

• Unopened Storage: Store refrigerated between 2°C and 8°C inside original packaging to shield solution from UV exposure.

• In-Use Handling: Return unit to cold storage (2°C–8°C) immediately following sample withdrawal.

• Thermal Notice: Avoid freezing liquid pen cartridges to prevent mechanical ring fracture or structural peptide degradation.

Mandatory Research Compliance Notice

• Strictly for Laboratory and Scientific Research Only: The ChemCo MOTS-c 20mg Pen is supplied strictly for in vitro laboratory research, analytical testing, and scientific study.

• Not for Human or Veterinary Administration: This product is explicitly prohibited from being used as a drug, human anti-aging therapy, cosmetic, medical device, or therapeutic substance.